Imagine how efficiently your delicate cell machinery operated in youth.
Young cells cleanse themselves of waste through a process that is highly dependent on an enzyme called AMPK.
Normal aging diminishes AMPK activity.
One toxic result is accumulation of cellular debris that interferes with vital cellular function.
AMPK deficit is also associated with excess cell proliferation.
Maturing people do not want excess cell proliferation. Rapidly dividing cells lead to greater DNA mutations along with buildup of arterial plaque and abdominal adiposity.
When AMPK is activated, it suppresses cell proliferation. This has powerful implications in the prevention of malignancies, atherosclerosis and obesity.
Activating AMPK also helps clear cells of “debris” that clogs their metabolic activity.
Reducing Abdominal Fat
AMPK deficit manifests outwardly as stored body fat, especially in the abdomen.
Boosting AMPK activity can remove fat by:
- Inhibiting triglyceride synthesis
- Inhibiting fatty-acid synthesis
- Inhibiting adipocyte (fat cell) proliferation
- Facilitating fat burning for energy
- Promoting healthy oxidation of fatty acids
- Improving insulin sensitivity
- Suppressing glucose synthesis in the liver
When AMPK is activated it forces cells to utilize stored fats.
Protecting Against Malignancies
Some studies have shown that activated AMPK turns on genes that suppress malignant cell transformation while promoting healthy longevity.
AMPK activation is a glucose-lowering mechanism of metformin. Metformin has been associated with 30%lower cancer incidence.
We know that insulin resistance, obesity, and excess blood glucose increase cancer risk and reduce longevity.